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Association of variants in renal salt reabsorption-related gene SLC12A3 with essential hypertension in a Mongolian population

J. Q. Liang, Xi, Y. G., An, C. Y., and Su, X. L., Association of variants in renal salt reabsorption-related gene SLC12A3 with essential hypertension in a Mongolian population, vol. 14, pp. 10026-10036, 2015.

Mounting evidence has implicated the SLC12A3 gene in essential hypertension. Here, we examined the potential associations of common variants of the SLC12A3 gene with blood pressure traits in Mongolians in China. Genomic DNA was extracted from 508 unrelated Mongolian patients with essential hypertension and 246 normotensive Mongolian subjects for genotyping. The genotype distributions of all selected polymorphisms were consistent with Hardy-Weinberg equilibrium.

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