susceptibility

Interleukin-10 promoter polymorphisms associated with susceptibility to lumbar disc degeneration in a Chinese cohort

W. P. Lin, Lin, J. H., Chen, X. W., Wu, C. Y., Zhang, L. Q., Huang, Z. D., and Lai, J. M., Interleukin-10 promoter polymorphisms associated with susceptibility to lumbar disc degeneration in a Chinese cohort, vol. 10, pp. 1719-1727, 2011.

We investigated a possible association between interleukin (IL)-10 single nucleotide polymorphisms (SNPs) and susceptibility to and severity of lumbar disc degeneration (LDD) in a Chinese cohort of 320 patients with LDD and 269 gender- and age-matched controls. The degree of disc degeneration was determined by magnetic resonance imaging using Schneiderman’s classification. Genetic analysis of IL-10 promoter polymorphisms (at -1082 A/G, -819 T/C, and -592 A/C) was carried out by PCR-RFLP.

Meta-analysis of an association of codon 72 polymorphisms of the p53 gene with increased endometrial cancer risk

Y. Gu, Zhou, X., and Zhang, S. L., Meta-analysis of an association of codon 72 polymorphisms of the p53 gene with increased endometrial cancer risk, vol. 10, pp. 3609-3619, 2011.

Polymorphisms of the p53 gene have been associated with susceptibility to endometrial cancer. However, whether there is a specific association is still controversial. We investigated a possible association between p53 codon 72 polymorphism and endometrial cancer risk by conducting a meta-analysis. Publications addressing this association were selected from the Pubmed, Embase and CBM databases (up to January 2011). Data were extracted from the studies by two independent reviewers. The meta-analysis was performed using RevMan 5.0.25 and STATA 9.2 softwares.

Detection of a resistance gradient to Passion fruit woodiness virus and selection of ‘yellow’ passion fruit plants under field conditions

C. B. M. Cerqueira-Silva, Moreira, C. N., Figueira, A. R., Corrêa, R. X., and Oliveira, A. C., Detection of a resistance gradient to Passion fruit woodiness virus and selection of ‘yellow’ passion fruit plants under field conditions, vol. 7, pp. 1209-1216, 2008.

Productivity of ‘yellow’ passion fruit (Passiflora edulis Sims. f. flavicarpa O. Deg.) is reduced by infection with Cowpea aphid-borne mosaic virus (CABMV). We examined resistance in 72 yellow passion fruit plants grown from open-pollinated commercial seed. Plants were mechanically inoculated with CABMV virus and maintained in the field in order to select contrasting genotypes for resistance.

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