Stem cell cultivation

Isolation, proliferation, and induction of Bama mini-pig spermatogonial stem cells in vitro

H. M. Zhao, Yang, H., Luo, F. H., Li, M. X., Zhang, S., Yang, X. G., Lu, Y. Q., Lu, S. S., Wu, Y. J., Lu, K. H., Zhao, H. M., Yang, H., Luo, F. H., Li, M. X., Zhang, S., Yang, X. G., Lu, Y. Q., Lu, S. S., Wu, Y. J., and Lu, K. H., Isolation, proliferation, and induction of Bama mini-pig spermatogonial stem cells in vitro, vol. 15, p. -, 2016.

Spermatogonial stem cells (SSCs), the unique seed cells of testes, can undergo meiosis and form spermatozoa, thus transmitting genetic information to offspring. Research concerning these cells explores the mechanism underlying spermatogenesis, making possible the induction of their differentiation into spermatozoa in vitro. SSCs have therefore attracted much interest among scientists. Although the proliferation of such cells in vitro has been demonstrated, we are unaware of any long-term laboratory culture of porcine SSCs.

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