Spinal cord injury

Protective effect and mechanism of probucol in the treatment of spinal cord injury

W. B. Zhu, Wang, Y. H., Sun, G. F., and Wu, J. H., Protective effect and mechanism of probucol in the treatment of spinal cord injury, vol. 14, pp. 8029-8037, 2015.

To investigate the effects of probucol on the treatment of spinal cord injury in rat, 80 rats were randomly divided into two groups of 40: a group treated with probucol and a control group. Allen’s method was used to establish a rat model of spinal cord injury. After establishment, probucol (500 mg·kg-1·day-1) was intraperitoneally injected into the treatment group rats for 1 week, while the same amount of saline was used to treat the control group.

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