Sperm quality

Effects of polymorphisms in the bovine growth differentiation factor 9 gene on sperm quality in Holstein bulls

K. Q. Tang, Yang, W. C., Zhang, X. X., and Yang, L. G., Effects of polymorphisms in the bovine growth differentiation factor 9 gene on sperm quality in Holstein bulls, vol. 12, pp. 2189-2195, 2013.

Members of the transforming growth factor-β (TGFβ) superfamily are critical regulators of germ cell development that act as extracellular ligands of the signal transduction pathways regulating proliferation, differentiation, apoptosis, and other aspects of cell behavior. Growth differentiation factor 9 (GDF9) is a member of the TGFβ superfamily that plays a critical role in ovarian follicular development and ovulation rate in females; however, its role in the testis has not been well elucidated.

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