Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts
“Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts”, vol. 12, pp. 6527-6534, 2013.
, The aim of this study was to observe the dynamic expression of osteopontin, type I collagen, and osteocalcin genes during the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteoblasts and confirm whether BMSCs can differentiate and mature into osteoblasts. A healthy, 2-month-old Altay tailed sheep was obtained, and 10 mL bone marrow was extracted from the posterior superior iliac spine of the sheep via puncture. Sheep BMSCs were extracted using a whole bone marrow culture method and cultured for osteogenic induction.