Sodium β-glycerophosphate

Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts

Y. Hu, Tang, X. - X., and He, H. - Y., Gene expression during induced differentiation of sheep bone marrow mesenchymal stem cells into osteoblasts, vol. 12, pp. 6527-6534, 2013.

The aim of this study was to observe the dynamic expression of osteopontin, type I collagen, and osteocalcin genes during the differentiation of bone marrow mesenchymal stem cells (BMSCs) into osteoblasts and confirm whether BMSCs can differentiate and mature into osteoblasts. A healthy, 2-month-old Altay tailed sheep was obtained, and 10 mL bone marrow was extracted from the posterior superior iliac spine of the sheep via puncture. Sheep BMSCs were extracted using a whole bone marrow culture method and cultured for osteogenic induction.

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