SNPs

Association between IGF2 and CYP21 gene polymorphisms and characteristics of economic interest in Nellore cattle

M. A. da Silva, Rios, A. F. L., Ramos, E. S., Lôbo, R. B., Oliveira, H. N., and de Freitas, M. A. R., Association between IGF2 and CYP21 gene polymorphisms and characteristics of economic interest in Nellore cattle, vol. 10, pp. 2140-2147, 2011.

We analyzed two single nucleotide polymorphisms (SNPs) of the IGF2 and CYP21 genes in Nellore cattle participating in the Brazilian Animal Breeding Program. The SNPs were found in exon 6 of the IGF2 (insulin-like growth factor 2) gene (RFLP/MboII) as well as in the promoter region of the CYP21 (steroid 21-hydroxylase) gene (RFLP/HpaII) of these animals. The TC heterozygotes were significantly more frequent than CC and TT homozygotes in the RFLP/MboII polymorphism.

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