SNPs

Characterization of SNPs in strawberry cultivars in China

A. J. Ge, Han, J., Li, X. D., Zhao, M. Z., Liu, H., Dong, Q. H., and Fang, J. G., “Characterization of SNPs in strawberry cultivars in China”, vol. 12, pp. 639-645, 2013.

Single nucleotide polymorphisms (SNPs) occur at high frequencies in both plant and animal genomes and can provide broad genome coverage and reliable estimates of genetic relationships. The availability of expressed sequence tag (EST) data has made it feasible to discover SNPs. DNA analysis is crucial in genetic studies not only for strawberry breeding programs but also for characterization of hybrids and species. We cloned 96 EST sequences, and 116 SNPs were discovered by comparing 16 strawberry cultivars grown in the region of Nanjing, China.

Impacts of single nucleotide polymorphisms and haplotypes in the bovine Dapper1 gene on body weight

J. Wang, Wang, C., Gao, Y., Lan, X. - Y., Lei, C. - Z., Wang, J. - Q., and Chen, H., “Impacts of single nucleotide polymorphisms and haplotypes in the bovine Dapper1 gene on body weight”, vol. 12, pp. 1254-1268, 2013.

The Dapper1 protein plays important role in multiple developmental processes via negative modulation of the Wnt signaling pathway. We detected variations in Dapper1 in 1185 individuals from 5 Chinese cattle breeds and determined their effects on bovine body weight. Two silent mutations (g.8344C>T and g.8428C>T) in exon 6 along with two substitutions (g.10513A>G and g.10765C>G) in the 3'-untranslated region were detected with DNA pool sequencing and forced polymerase chain reaction-restriction fragment length polymorphism.

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