SNP polymorphism

Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene

Y. F. Liu, Zan, L. S., Cui, W. T., Xin, Y. P., Jiao, Y., and Li, K., Molecular cloning, characterization and association analysis of the promoter region of the bovine CDK6 gene, vol. 10, pp. 1777-1786, 2011.

Cyclin-dependent kinase 6 (CDK6) is a key element of D-type cyclin holoenzymes. It is involved in the regulation of the G1-phase of the cell cycle and is considered to be an important candidate gene for selection of body measurement traits through marker-assisted selection. We cloned the promoter sequence of this gene in bovines and found it to share high similarity with that of the human CDK6 promoter.

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