SNP

Identification of SNPs in growth-related genes in Colombian creole cattle

R. Martínez, Rocha, J. F., Bejarano, D., Gómez, Y., Abuabara, Y., Gallego, J., Martínez, R., Rocha, J. F., Bejarano, D., Gómez, Y., Abuabara, Y., and Gallego, J., Identification of SNPs in growth-related genes in Colombian creole cattle, vol. 15, p. -, 2016.

Colombian creole cattle have important adaptation traits related to heat tolerance and reproductive and productive efficiency. Romosinuano (ROMO) and Blanco Orejinegro (BON) are the most common breeds used by Colombian cattle breeders. Growth traits are of prime importance in these animals, which are mainly raised for beef production. Genes encoding growth hormone, growth hormone receptor, homeobox protein, insulin growth factor binding protein 3, leptin, and myostatin have been associated with physiological growth pathways in cattle and other species.

Identification of SNPs located on BTA 6 and BTA 20 significantly associated with bovine respiratory disease in crossbred cattle

S. L. Miller, Mizell, S., Walker, R., Page, T., Garcia, M. D., Miller, S. L., Mizell, S., Walker, R., Page, T., and Garcia, M. D., Identification of SNPs located on BTA 6 and BTA 20 significantly associated with bovine respiratory disease in crossbred cattle, vol. 15, p. -, 2016.

The objective of the present study was to evaluate single nucleotide polymorphisms (SNPs) located in two quantitative trait locus (QTL) regions (BTA 6 and BTA 20) that are associated with bovine respiratory disease (BRD). A population of 323 crossbred steers sired by five purebred sire breeds during 2010-2013 (Angus, Braford, Braunvieh, Charolais, and Simmental) were evaluated for BRD susceptibility during the finishing process at a commercial feedlot.

Polymorphism in the melatonin receptor gene in buffalo populations of the Brazilian Amazon

E. B. Machado, Souza, B. B., Guimarães, R. C., Azevedo, J. S. N., Gonçalves, E. C., Ribeiro, H. F. L., Filho, S. T. Rolim, E. Filho, S., Machado, E. B., Souza, B. B., Guimarães, R. C., Azevedo, J. S. N., Gonçalves, E. C., Ribeiro, H. F. L., Filho, S. T. Rolim, and E. Filho, S., Polymorphism in the melatonin receptor gene in buffalo populations of the Brazilian Amazon, vol. 15, p. -, 2016.

Buffalo farming in Brazil is increasing, as is the challenge of identifying molecular markers that will improve productivity. Therefore, the aim of this study was to analyze single nucleotide polymorphisms of the receptor gene for the hormone melatonin in buffaloes from northern Brazil by polymerase chain reactions (PCRs) and restriction fragment length polymorphism assays. The PCR products exhibited a cutting point for HpaI at the 318th position of the gene, indicating a transition substitution (T↔C).

A single nucleotide polymorphism in GABAA receptor isoforms is potentially responsible for isoflurane sensitivity in mice

X. Wang, Song, Z. G., Huang, D. X., Gao, H., Wang, Q., Wang, Z. P., Wang, X., Song, Z. G., Huang, D. X., Gao, H., Wang, Q., and Wang, Z. P., A single nucleotide polymorphism in GABAA receptor isoforms is potentially responsible for isoflurane sensitivity in mice, vol. 15, p. -, 2016.

GABAA receptors are chloride channels in the brain that are activated by binding with g-aminobutyric acid (GABA). The cDNA sequences of GABAA receptor subunits from two strains of mice with different sensitivities to isoflurane were compared to identify nucleotide mutations. Included 80 mice from two strains with different sensitivities to isoflurane on C57BL/6 background. Forty mice were from an isoflurane-sensitive strain (S group) and 40 mice were from a resistant strain (R group).

Synonymous single nucleotide polymorphisms in the MC4R gene that are significantly associated with milk production traits in water buffaloes

T. X. Deng, Pang, C. Y., Liu, M. Q., Zhang, C., Liang, X. W., Deng, T. X., Pang, C. Y., Liu, M. Q., Zhang, C., and Liang, X. W., Synonymous single nucleotide polymorphisms in the MC4R gene that are significantly associated with milk production traits in water buffaloes, vol. 15, p. -, 2016.

Melanocortin-4 receptor (MC4R) is associated with feed intake, growth, fatness, and carcass composition in many domestic animals. The aim of this study was to evaluate the association of single nucleotide polymorphisms (SNPs) in MC4R with milk production traits in water buffalo. Eight SNPs were identified by direct polymerase chain reaction sequencing of samples from 18 buffaloes. SNPs were then genotyped using the matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) method in 332 buffaloes.

A simple real-time polymerase chain reaction (PCR)-based assay for authentication of the Chinese Panax ginseng cultivar Damaya from a local ginseng population

H. Wang, Wang, J., Li, G., Wang, H., Wang, J., and Li, G., A simple real-time polymerase chain reaction (PCR)-based assay for authentication of the Chinese Panax ginseng cultivar Damaya from a local ginseng population, vol. 15, p. -, 2016.

Panax ginseng is one of the most important medicinal plants in the Orient. Owing to its increasing demand in the world market, cultivated ginseng has become the main source of medicinal material. Among the Chinese ginseng cultivars, Damaya commands higher prices and is grown in significant proportions among the local ginseng population. Due to the lack of rapid and accurate authentication methods, Damaya is distributed among different cultivars in the local ginseng population in China.

Novel polymorphism in exon 1 of the melatonin receptor gene unassociated with reproductive characteristics of buffaloes in the Amazon Region

E. M. Barbosa, Souza, B. B., Guimarães, R. C., Azevedo, J. S. N., Gonçalves, E. C., Ribeiro, H. F. L., Filho, S. T. Rolim, E. Filho, S., Barbosa, E. M., Souza, B. B., Guimarães, R. C., Azevedo, J. S. N., Gonçalves, E. C., Ribeiro, H. F. L., Filho, S. T. Rolim, and E. Filho, S., Novel polymorphism in exon 1 of the melatonin receptor gene unassociated with reproductive characteristics of buffaloes in the Amazon Region, vol. 15, p. -, 2016.

The objective of this study was to sequence part of the exon 1 in the melatonin receptor 1A gene (MTRN1A) in buffaloes to detect a novel polymorphism with which to associate reproductive characteristics, such as age at first birth and the interval between births, in buffaloes from the northeastern region of the State of Pará (Brazil). Buffalo hair samples (77) were collected from the Terra Firme region of Pará. DNA was extracted and polymerase chain reactions (PCRs) were carried out with a primer that was designed using the GenBank accession No. AY524665 reference sequence.

Novel polymorphism in exon 1 of the melatonin receptor gene unassociated with reproductive characteristics of buffaloes in the Amazon Region

E. M. Barbosa, Souza, B. B., Guimarães, R. C., Azevedo, J. S. N., Gonçalves, E. C., Ribeiro, H. F. L., Filho, S. T. Rolim, and E. Filho, S., Novel polymorphism in exon 1 of the melatonin receptor gene unassociated with reproductive characteristics of buffaloes in the Amazon Region, vol. 15, p. -, 2016.

The objective of this study was to sequence part of the exon 1 in the melatonin receptor 1A gene (MTRN1A) in buffaloes to detect a novel polymorphism with which to associate reproductive characteristics, such as age at first birth and the interval between births, in buffaloes from the northeastern region of the State of Pará (Brazil). Buffalo hair samples (77) were collected from the Terra Firme region of Pará. DNA was extracted and polymerase chain reactions (PCRs) were carried out with a primer that was designed using the GenBank accession No. AY524665 reference sequence.

Polymorphisms in the nuclear factor kappa B gene association with recurrent embryo implantation failure

L. Luo, Li, D. H., Li, X. P., Zhang, S. C., Yan, C. F., Wu, J. F., Qi, Y. H., Zhao, J., Luo, L., Li, D. H., Li, X. P., Zhang, S. C., Yan, C. F., Wu, J. F., Qi, Y. H., Zhao, J., Luo, L., Li, D. H., Li, X. P., Zhang, S. C., Yan, C. F., Wu, J. F., Qi, Y. H., and Zhao, J., Polymorphisms in the nuclear factor kappa B gene association with recurrent embryo implantation failure, vol. 15, p. -, 2016.

Despite more than a century of intensive study, the mechanisms of successful pregnancy remain unclear. Recent research suggests that NF-κB (nuclear factor kappa B) plays an important role in embryo implantation. In the current study, we aimed to identify SNPs that contribute to genetic susceptibility for recurrent implantation failure (RIF). Thus, we examined the potential associations between RIF and ten SNPs (rs28362491, rs3774932, rs1598856, rs230528, rs230521, rs3774956, rs4648055, rs3774964, rs4648068, and rs3774968) of the NF-κB gene.

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