SNP

Identification and characterization of RFRP gene in pigs and its association with reproductive traits

M. X. Fang, Huang, Y. S., Ye, J., Zhang, W., Li, Y., and Nie, Q. H., Identification and characterization of RFRP gene in pigs and its association with reproductive traits, vol. 13, pp. 1661-1671, 2014.

RFamide-related peptide (RFRP) gene is a crucial gene of the hypothalamo-pituitary-gonadal axis and plays an important role in reproduction regulation. This study aimed to clone and characterize the pig RFRP gene. We obtained a 645-bp cDNA of pig RFRP gene comprising a 546-bp open reading frame, which encoded a peptide of 188 amino acids. The pig RFRP coding sequences have the identities of 81, 68.8, and 76.1% with their counterparts in humans, mice, and rats, respectively.

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