Smoking habits

Association between RsaI polymorphism in estrogen receptor β gene and male infertility

B. M. Bordin and Moura, K. K. V. O., Association between RsaI polymorphism in estrogen receptor β gene and male infertility, vol. 14, pp. 10954-10960, 2015.

The estrogen receptor β (ERβ) gene plays an important role in the regulation of fertility in both males and females. The RsaI polymorphism in ERβis associated with male infertility in Caucasian patients. The aim of this study was to investigate the frequency of this polymorphism in the etiology of idiopathic male infertility and its correlation with smoking habits. We analyzed 287 Brazilian men, including 161 infertile and 126 fertile men, to evaluate the association between the RsaI polymorphism and male infertility.

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