Small-for-size syndrome

Development of an improved rat model of dual graft liver transplantation with long-term survival

X. - J. Xie, Ye, Y. - F., He, Y., Xie, H. - Y., Zhou, L., Wang, Y., Xing, C. - Y., and Zheng, S. - S., Development of an improved rat model of dual graft liver transplantation with long-term survival, vol. 13, pp. 8035-8045, 2014.

Dual graft liver transplantation has been demonstrated to be feasible as well as effective in increasing the donor pool and in preventing the potential for small-for-size syndrome. However, little is known about the pathophysiological and immune processes following dual graft liver transplantation due to the lack of appropriate animal models. The aim of this study, therefore, was to establish an improved rat model of dual graft liver transplantation, with long-term survival. Male inbred rats were used as both donors and recipients.

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