Single nucleotide polymorphisms

Efficient human paternity testing with a panel of 40 short insertion-deletion polymorphisms

J. R. Pimenta and Pena, S. D. J., Efficient human paternity testing with a panel of 40 short insertion-deletion polymorphisms, vol. 9, pp. 601-607, 2010.

We developed a panel of 40 multiplexed short insertion-deletion (indel) polymorphic loci with widespread chromosomal locations and allele frequencies close to 0.50 in the European population. We genotyped these markers in 360 unrelated self-classified White Brazilians and 50 mother-child-probable father trios with proven paternity. The average heterozygosity (gene diversity) per locus was 0.48, and the combined probability of identity (matching probability) for the 40-locus set was 3.48 x 10-17. The combined power of exclusion of the indel panel was 0.9997.

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