Single nucleotide polymorphism

Association of the IL-4R Q576R polymorphism and asthma in the Chinese Han population: A meta-analysis

Z. Y. Huang, Cheng, B. J., Cai, G. J., and Zhang, B. F., Association of the IL-4R Q576R polymorphism and asthma in the Chinese Han population: A meta-analysis, vol. 14, pp. 2900-2911, 2015.

The IL-4R Q576R polymorphism has been reported to increase susceptibility to asthma, but the results are controversial. Thus, we performed a meta-analysis to evaluate the association of the IL-4R Q576R polymorphism and asthma risk in the Chinese Han population. A total of sixteen eligible case-control studies that evaluated the relationship between the IL-4R Q576R polymorphism and asthma in the Chinese Han population were obtained by comprehensive literature search incorporating electronic databases, and included 2077 asthma cases and 1589 controls.

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