Single nucleotide polymorphism

Functional polymorphisms in microRNAs and susceptibility to liver cancer: a meta-analysis and meta-regression

B. S. Wang, Liu, Z., Xu, W. X., and Sun, S. L., Functional polymorphisms in microRNAs and susceptibility to liver cancer: a meta-analysis and meta-regression, vol. 13, pp. 5426-5440, 2014.

MicroRNAs (miRNAs) are small non-coding RNA molecules that play a fundamental role in controlling a variety of biological functions. Emerging evidence has shown that common genetic polymorphisms in miRNAs may be associated with the development of liver cancer; however, several individually published studies showed inconclusive results. This meta-analysis aimed to derive a more precise estimation of the association between functional polymorphisms in miRNAs and susceptibility to liver cancer.

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