Single nucleotide polymorphism

Genetic association of UBE2B variants with susceptibility to male infertility in a Northeast Chinese population

Y. Hu, Wen, W., Yu, J. - G., Qu, S. - Q., Wang, S. - S., Liu, J., Li, B. - S., and Luo, Y., Genetic association of UBE2B variants with susceptibility to male infertility in a Northeast Chinese population, vol. 11, pp. 4226-4234, 2012.

The ubiquitin-conjugating enzyme 2B gene (UBE2B) is involved in the regular and symmetric organization of the fibrous sheath of sperm flagella. This study aimed to examine the relationship between single nucleotide polymorphisms (SNPs) in UBE2B and infertility in Northeast Chinese men. We carried out a polymerase chain reaction-restriction fragment length polymorphism analysis for SNPs in 312 fertile males and 388 infertile males in Northeast China.

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