Signaling pathways

Application of the ERK signaling pathway inhibitor PD98059 in long-term in vivo experiments

X. Y. Chen, Cai, H. Z., Wang, X. Y., Chen, Q. Y., Yang, H., Chen, Y. J., and Tang, Y. P., Application of the ERK signaling pathway inhibitor PD98059 in long-term in vivo experiments, vol. 14, pp. 18325-18333, 2015.

The aim of this study was to explore methods by which the ERK signaling pathway inhibitor PD98059 (PD) could be used in long-term in vivo experiments. Forty healthy New Zealand rabbits were randomly divided into blank control, model control, PD low-dose, PD high-dose, PD blank, dimethyl sulfoxide (DMSO) control, DMSO blank, and positive control groups.

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