Side population

Effects of bisphenol A on decreasing the percentage and promoting the growth of stem cell-like cells from SK-N-SH human neuroblastoma cells

J. C. Zheng, Qi, S. Q., Yang, L., Ma, Y. Y., Dong, K. R., Zhu, H. T., Yang, S. B., Xu, T., Zheng, S., and Xiao, X. M., Effects of bisphenol A on decreasing the percentage and promoting the growth of stem cell-like cells from SK-N-SH human neuroblastoma cells, vol. 14, pp. 2986-2993, 2015.

Bisphenol A (BPA) is an industrial contaminant and is reported to be a risk factor associated with the development of tumors. In our previous studies, we have shown that BPA promoted the growth of SK-N-SH human neuroblastoma cells and increased their invasion and metastasis. In this study, we further investigated the effects of BPA and 17β-estradiol (E2) on the stem cell-like cells from SK-N-SH cells.

Isolation and characterization of cancer stem cells from medulloblastoma

J. Liu, Chi, N., Zhang, J. Y., Zhu, W., Bian, Y. S., and Chen, H. G., Isolation and characterization of cancer stem cells from medulloblastoma, vol. 14, pp. 3355-3361, 2015.

Brain cancer stem cells are a subset of tumor cells present in several types of brain tumor that evade treatment regimens and are responsible for tumor recurrence. Recent reports on several tumors have suggested that Hoechst 33342 dye exclusion is a powerful technique for isolating cancer stem cell-like side population (SP) cells. In the present study, we attempted to isolate the SP cells from medulloblastoma, a malignant brain tumor in children. The tumor samples obtained were subjected to fluorescence-activated cell sorting analysis for SP cell isolation.

Subscribe to Side population