Sequence diversity

Genomic characterization and sequence diversity of the β2-microglobulin gene in the miiuy croaker, Miichthys miiuy

Y. N. Sun, Su, X. R., Xu, T. J., and Li, T. W., Genomic characterization and sequence diversity of the β2-microglobulin gene in the miiuy croaker, Miichthys miiuy, vol. 14, pp. 10249-10257, 2015.

β2-Microglobulin (β2m) is related to major histocompatibility complex class I alpha chains, and forms cell-surface glycoproteins that mediate a variety of functions in immune defense. In general, β2m has no isoforms and is not polymorphic in higher vertebrates, but polymorphisms between different alleles have been found in some fish species. In this study, full-length β2m cDNA and genomic sequences were cloned from the miiuy croaker (Miichthys miiuy).

Sequence variation in ROP8 gene among Toxoplasma gondii isolates from different hosts and geographical localities

Z. Y. Li, Chen, J., Lu, J., Wang, C. R., and Zhu, X. Q., Sequence variation in ROP8 gene among Toxoplasma gondii isolates from different hosts and geographical localities, vol. 14, pp. 11403-11409, 2015.

The protozoan parasite Toxoplasma gondii has a worldwide distribution; it can cause serious diseases in humans and almost all other warm-blooded animals. Different genotypes of T. gondii result in different lesions in the same host. T. gondii rhoptry protein 8 (TgROP8) is a major factor of T. gondii acute virulence. We examined sequence variation in the TgROP8 gene among T. gondii isolates from different hosts and geographical localities. The TgROP8 gene was amplified from individual isolates and sequenced.

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