Rs2230199

Association between a functional genetic polymorphism (rs2230199) and age-related macular degeneration risk: a meta-analysis

M. X. Zhang, Zhao, X. F., Ren, Y. C., Geng, T. T., Yang, H., Feng, T., Jin, T. B., and Chen, C., Association between a functional genetic polymorphism (rs2230199) and age-related macular degeneration risk: a meta-analysis, vol. 14, pp. 12567-12576, 2015.

The association between the rs2230199 C>G single nucleotide polymorphism (SNP) in complement component 3 and age-related macular degeneration (AMD) risk has been examined extensively but the results are not consistent among studies. The aim of this study was to perform a meta-analysis of all available studies on this SNP in relation to AMD. The comprehensive databases of PubMed, Medline, Web of Knowledge, CNKI, and Google Scholar were searched for case-control studies investigating the association between the rs2230199 polymorphism and AMD susceptibility.

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