Risk factors

TGF-β1 polymorphisms and familial aggregation of liver cancer in Guangxi, China

P. Q. Wan, Wu, J. Z., Huang, L. Y., Wu, J. L., Wei, Y. H., and Ning, Q. Y., TGF-β1 polymorphisms and familial aggregation of liver cancer in Guangxi, China, vol. 14, pp. 8147-8160, 2015.

The goal of present study was to investigate the relationship between polymorphisms of TGF-β1 and familial aggregation of liver cancer in Guangxi Zhuang, Han, and Yao populations. We conducted a population-based case-control family study of liver cancer in Guanxi, China. A total of 214 individuals from 37 case families were surveyed for polymorphisms in TGF-β1. We genotyped six functional TGF-β1 polymorphisms: rs1800469, rs2241715, rs2241716, rs11466345, rs8105161, and rs747857.

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