Risk

CYP1A2-163C/A (rs762551) polymorphism and bladder cancer risk: a case-control study

Y. L. Song, Wang, L., Ren, J. C., Xu, Z. H., Song, Y. L., Wang, L., Ren, J. C., Xu, Z. H., Song, Y. L., Wang, L., Ren, J. C., and Xu, Z. H., CYP1A2-163C/A (rs762551) polymorphism and bladder cancer risk: a case-control study, vol. 15, p. -, 2016.

To date, no study has investigated the association between CYP1A2-163C/A polymorphism and bladder cancer risk in a Chinese population. Here, we extracted genomic DNA from peripheral white blood cells, and differentiated CYP1A2 alleles by polymerase chain reaction-based restriction fragment length polymorphism methods. Differences in genotype frequencies between the cases and controls were evaluated using a chi-square test. The odds ratio (OR) and its 95% confidence interval (CI) were calculated using an unconditional logistic regression model.

DNA methyltransferase 3B -149C/T polymorphism and the risk of laryngeal squamous cell carcinoma: a case-control study

X. M. Zhang, Li, S., and Zhang, Q. M., DNA methyltransferase 3B -149C/T polymorphism and the risk of laryngeal squamous cell carcinoma: a case-control study, vol. 14, pp. 12866-12871, 2015.

A variety of molecular epidemiological studies have been conducted to examine the association between the DNMT3B -149C/T polymorphism and cancer susceptibility; however, there has been no study investigating the association between the DNMT3B -149C/T polymorphism and the risk of laryngeal squamous cell carcinoma (LSCC) until now. To determine the role of the DNMT3B -149C/T polymorphism in LSCC, we genotyped 113 patients with LSCC and 110 controls from a Chinese population using polymerase chain reaction-restriction fragment length polymorphism analysis.

Association between MTHFR 677C/T and 1298A/C gene polymorphisms and breast cancer risk

X. F. Zhang, Liu, T., Li, Y., and Li, S., Association between MTHFR 677C/T and 1298A/C gene polymorphisms and breast cancer risk, vol. 14, pp. 16425-16430, 2015.

We performed a case-control study to investigate the association between single nucleotide polymorphisms in the MTHFR gene (677C/T and 1298A/C) and risk of breast cancer. This case-control study included 216 breast cancer cases and 216 controls. The MTHFR 677C/T and 1298A/C gene polymorphisms were assessed by polymerase chain reaction restriction fragment length polymorphism.

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