Reproductive performance

Molecular characterization, expression, polymorphism of NR5A2 and its relationship with litter size in Hu sheep

Y. X. Li, Zhang, J., Qian, Y., Meng, C. H., Wang, H. L., Tao, X. J., Zhong, S., Cao, S. X., and Li, Q. F., “Molecular characterization, expression, polymorphism of NR5A2 and its relationship with litter size in Hu sheep”, vol. 14, pp. 12765-12775, 2015.

NR5A2 has been implicated in processes as diverse as steroidogenesis, cellular proliferation, ovarian follicular development, ovulation, and fertility in mammals. However, data about the relationship between NR5A2 and prolificacy in mammals are lacking. In the present study, we identified and characterized NR5A2 of Hu sheep, and investigated the correlation between NR5A2 and reproductive performance. The full-length coding region was 1488 bp, and the gene was conserved in mammals.

Male carriers of balanced reciprocal translocations in Northeast China: sperm count, reproductive performance, and genetic counseling

H. G. Zhang, Wang, R. X., Li, L. L., Sun, W. T., Zhang, H. Y., and Liu, R. Z., “Male carriers of balanced reciprocal translocations in Northeast China: sperm count, reproductive performance, and genetic counseling”, vol. 14, pp. 18792-18798, 2015.

Balanced chromosomal translocations in men can cause failure of spermatogenesis owing to meiotic impairment. Male carriers may exhibit normozoospermia, although clinical manifestations can include oligozoospermia or azoospermia, oligozoospermia or normozoospermia. Here, we reported the characteristics of balanced reciprocal translocations in men from northeastern China, and explored the relationship between sperm count and reproductive performance, to enable informed genetic counseling. The frequency of balanced reciprocal translocations was found to be 1.62%.

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