Replication timing

Replication timing regulation in adults with chromosomal balance rearrangements

Y. Xie, Wu, J., Lin, S., Zhou, Y., Fang, Q., and Sun, X., Replication timing regulation in adults with chromosomal balance rearrangements, vol. 14, pp. 7833-7840, 2015.

The alternative forms of the alleles in biallelic genes display a synchronous pattern of replication that is different from genes subjected to monoallelic expression, which exhibit an asynchronous mode of replication. The present study sought to gain insight into changes in the allele-specific replication timing in phenotypically normal humans with balanced chromosomal rearrangements, and to investigate the potential mechanism for chromosomal rearrangements.

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