Repetitive genome assembly

A repetitive sequence assembler based on next-generation sequencing

S. Lian, Tu, Y., Wang, Y., Chen, X., Wang, L., Lian, S., Tu, Y., Wang, Y., Chen, X., and Wang, L., A repetitive sequence assembler based on next-generation sequencing, vol. 15, p. -, 2016.

Repetitive sequences of variable length are common in almost all eukaryotic genomes, and most of them are presumed to have important biomedical functions and can cause genomic instability. Next-generation sequencing (NGS) technologies provide the possibility of identifying capturing these repetitive sequences directly from the NGS data. In this study, we assessed the performances in identifying capturing repeats of leading assemblers, such as Velvet, SOAPdenovo, SGA, MSR-CA, Bambus2, ALLPATHS-LG, and AByss using three real NGS datasets.

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