Functional characterization of genetic variants in the porcine TLR3 gene
“Functional characterization of genetic variants in the porcine TLR3 gene”, vol. 13, pp. 1348-1357, 2014.
, Toll-like receptor 3 (TLR3) recognizes double-stranded RNA, which is a molecular signature of viruses, and plays a pivotal role in host defense against viral invasion. Polymorphisms in the human TLR3 gene have been shown to affect the receptor function and to be associated with a variety of diseases, suggesting correlations between TLR3 polymorphisms and the disease resistance/susceptibility in pigs.