Serum soluble RAGE level inversely correlates with left ventricular hypertrophy in essential hypertension patients
“Serum soluble RAGE level inversely correlates with left ventricular hypertrophy in essential hypertension patients”, vol. 15, p. -, 2016.,
Soluble receptor for advanced glycation end-products (sRAGE) acts as a decoy to prevent interaction between RAGE and its pro-inflammatory ligands. sRAGE levels have been found to decrease in chronic inflammatory diseases, including hypertension. However, few data have been reported concerning the association between serum sRAGE levels and hypertensive left ventricular hypertrophy (LVH). Fasting blood samples were obtained from 209 essential hypertensive patients, and sRAGE levels were measured using a commercially available double-sandwich enzyme-linked immunosorbent assay kit.