Rapid acetylator genotype

Association of N-acetyltransferase-2 polymorphism with an increased risk of coronary heart disease in a Chinese population

J. D. Sun, Yuan, H., Hu, H. Q., Yu, H. M., Sun, J. D., Yuan, H., Hu, H. Q., and Yu, H. M., Association of N-acetyltransferase-2 polymorphism with an increased risk of coronary heart disease in a Chinese population, vol. 15, p. -, 2016.

We investigated the possible correlations between N-acetyltransferase-2 (NAT2) gene polymorphisms and the risk of coronary heart disease (CHD). CHD patients (113) and healthy controls (118) were enrolled from the First People’s Hospital of Yuhang between January 2013 and June 2014. The patients were divided into mild CHD (N = 72) and severe CHD (N = 41) subgroups. DNA samples were extracted and the distributions of NAT2 polymorphisms were examined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).

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