R-spondin1

Molecular cloning and tissue distribution profiles of the chicken R-spondin1 gene

Y. Q. Han, Geng, J., Shi, H. T., Zhang, X. M., Du, L. L., Liu, F. T., Li, M. M., Wang, X. T., Wang, Y. Y., and Yang, G. Y., Molecular cloning and tissue distribution profiles of the chicken R-spondin1 gene, vol. 14, pp. 3090-3097, 2015.

Rspo1 belongs to the Rspo family, which is composed of 4 members (Rspo1-4) that share 40 to 60% sequence homology and similar domain organizations, and regulate the WNT signaling pathway via a common mechanism. Rspo1 plays a key role in vertebrate development and is an effective mitogenic factor of gastrointestinal epithelial cells. We report the cloning of chicken Rspo1 and its gene expression distribution among tissues.

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