Evaluation of window cohabitation of DNA sequencing errors and lowest PHRED quality values
“Evaluation of window cohabitation of DNA sequencing errors and lowest PHRED quality values”, vol. 3, pp. 483-492, 2004.,
When analyzing sequencing reads, it is important to distinguish between putative correct and wrong bases. An open question is how a PHRED quality value is capable of identifying the miscalled bases and if there is a quality cutoff that allows mapping of most errors. Considering the fact that a low quality value does not necessarily indicate a miscalled position, we decided to investigate if window-based analyses of quality values might better predict errors.