Psoriasis

The common CARD14 gene missense polymorphism rs11652075 (c.C2458T/p.Arg820Trp) is associated with psoriasis: a meta-analysis

G. Shi, Li, S. J., Wang, T. T., Cheng, C. M., Fan, Y. M., Zhu, K. J., Shi, G., Li, S. J., Wang, T. T., Cheng, C. M., Fan, Y. M., and Zhu, K. J., The common CARD14 gene missense polymorphism rs11652075 (c.C2458T/p.Arg820Trp) is associated with psoriasis: a meta-analysis, vol. 15, p. -, 2016.

Recent genetic evidence suggests a robust association of the CARD14 single nucleotide polymorphism rs11652075 (c.C2458T/p.Arg820Trp) and other rare mutations in this gene with psoriasis. To assess whether combined data support the relationship between CARD14 rs11652075 and susceptibility to this disease, we conducted a meta-analysis. PubMed (MEDLINE), EMBASE, Web of Science, and the Cochrane Library were searched for relevant papers published in English. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using random-effect models.

Correlation between serum IL-16 and atopic dermatitis

H. Y. Zheng, Zhao, L., Li, C. X., Li, S. H., Zheng, H. Y., Zhao, L., Li, C. X., Li, S. H., Zheng, H. Y., Zhao, L., Li, C. X., and Li, S. H., Correlation between serum IL-16 and atopic dermatitis, vol. 15, p. -, 2016.

This study aims to investigate the correlation between allergic sensitization of atopic dermatitis (AD) patients and their serum interleukin (IL)-16 levels. AD patients, healthy volunteers, and patients with psoriasis (N = 80, 35, 20, respectively) were tested for serum IL-16 and total and specific IgE levels by enzyme-linked immunosorbent assay, along with eosinophil counts. Serum allergen-specific IgE levels were determined, and skin-prick testing conducted in a subgroup of 45 AD patients.

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