Psoriasis

The common CARD14 gene missense polymorphism rs11652075 (c.C2458T/p.Arg820Trp) is associated with psoriasis: a meta-analysis

G. Shi, Li, S. J., Wang, T. T., Cheng, C. M., Fan, Y. M., Zhu, K. J., Shi, G., Li, S. J., Wang, T. T., Cheng, C. M., Fan, Y. M., and Zhu, K. J., The common CARD14 gene missense polymorphism rs11652075 (c.C2458T/p.Arg820Trp) is associated with psoriasis: a meta-analysis, vol. 15, p. -, 2016.

Recent genetic evidence suggests a robust association of the CARD14 single nucleotide polymorphism rs11652075 (c.C2458T/p.Arg820Trp) and other rare mutations in this gene with psoriasis. To assess whether combined data support the relationship between CARD14 rs11652075 and susceptibility to this disease, we conducted a meta-analysis. PubMed (MEDLINE), EMBASE, Web of Science, and the Cochrane Library were searched for relevant papers published in English. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using random-effect models.

Meta-analysis of IL-6 -174G/C polymorphism and psoriasis risk

G. Nie, Xie, C. L., Cao, Y. J., Xu, M. M., Shi, X., Zou, A. L., Qi, J. H., Nie, G., Xie, C. L., Cao, Y. J., Xu, M. M., Shi, X., Zou, A. L., and Qi, J. H., Meta-analysis of IL-6 -174G/C polymorphism and psoriasis risk, vol. 15, p. -, 2016.

Previous studies examining the association between interleukin-6 (IL-6) -174G/C polymorphism and psoriasis risk have produced inconsistent results. The aim of this study was to offer a comprehensive review of the association between IL-6 -174G/C polymorphism and psoriasis risk through a meta-analysis. Literature search of PubMed and Embase databases was conducted to identify all eligible studies published before October 29, 2015. Four case-control studies involving 651 psoriasis cases and 552 controls were included in this meta-analysis.

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