Psoriasis

Effect of NB-UVB on levels of MCP-1 and CCR6 mRNA in patients with psoriasis vulgaris

M. L. Gao and Wang, A. G., Effect of NB-UVB on levels of MCP-1 and CCR6 mRNA in patients with psoriasis vulgaris, vol. 14, pp. 12137-12144, 2015.

The aim of this study is to explore the effect of narrow band ultraviolet B (NB-UVB) on the chemokine receptor CCR6 mRNA levels in patients with psoriasis. Psoriasis area and severity index (PASI) values were recorded before and after the treatment with NB-UVB phototherapy of 30 psoriasis vulgaris patients. The reverse transcription-polymerase chain reaction method was used to detect the expression level of CCR6 mRNA in peripheral blood mononuclear cells, and compared with 30 healthy subjects.

Vascular endothelial growth factor gene polymorphisms and psoriasis susceptibility: a meta-analysis

Y. H. Lee and Song, G. G., Vascular endothelial growth factor gene polymorphisms and psoriasis susceptibility: a meta-analysis, vol. 14, pp. 14396-14405, 2015.

The aim of this study was to explore whether vascular endothelial growth factor (VEGF) polymorphisms confer susceptibil­ity to psoriasis. Meta-analyses were conducted to examine the asso­ciations between the +405 C/G, -460 C/T, -1154 A/G, and -2578 A/C polymorphisms of VEGF and psoriasis using allele contrast and reces­sive, dominant, and additive models. Seven studies on VEGF polymor­phisms and psoriasis involving 1956 subjects (psoriasis patients 665, controls 1291) were included in this meta-analysis.

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