Identification of altered pathways in hypertrophic cardiomyopathy based on combined data of protein-protein interactions and molecular pathways
The purpose of our study was to identify molecular pathways altered during the pathogenesis of hypertrophic cardiomyopathy (HCM) based on data from the STRING protein-protein interaction (PPI) database and the REACTOME pathway database. Identification of differentially expressed genes (DEGs) was carried out, followed by construction of a targeted network and selection of hub genes in this network.