Protein expression

Clinical significance of CTHRC1 protein expression in human cancers: a meta-analysis

S. F. Wang, Yin, Z., Yin, J. J., Zhang, W., Dong, C. G., Wang, S. F., Yin, Z., Yin, J. J., Zhang, W., and Dong, C. G., “Clinical significance of CTHRC1 protein expression in human cancers: a meta-analysis”, vol. 15, p. -, 2016.

The aim of this meta-analysis was to investigate the overall diagnostic and prognostic values of CTHRC1 expression in human cancer development. Based on the inclusion and exclusion criteria, 8 cohort studies were included in the meta-analysis. The data were extracted, and analyses were performed using a random-effects model. Summary odds ratios (ORs) and effect sizes (ESs) with 95% confidence intervals (CIs) were calculated to assess the strength of the associations. A total of 1065 cancer patients from the 8 studies were included in the meta-analysis.

Elevated expression of CXCR4 and correlation with clinicopathological features and prognosis of non-small cell lung cancer patients: a meta-analysis

H. Wang, Xie, F., Hu, Z., and Chen, L., “Elevated expression of CXCR4 and correlation with clinicopathological features and prognosis of non-small cell lung cancer patients: a meta-analysis”, vol. 14, pp. 17893-17903, 2015.

The specific correlation between CXCR4 expression and survival in non-small cell lung cancer (NSCLC) has been investigated independently; however, these have yielded inconsistent results. Therefore, we examined the exact relationship between CXCR4 expression and NSCLC in this meta-analysis. The bibliographic databases in English and Chinese were carefully searched and data regarding the prognostic value of CXCR4 and its association with pathological parameters of NSCLC were collected. Pooled odds ratios (OR) with 95% confidence interval (CI) were applied.

Correlation of increased MALAT1 expression with pathological features and prognosis in cancer patients: a meta-analysis

X. S. Shi, Li, J., Yang, R. H., Zhao, G. R., Zhou, H. P., Zeng, W. X., and Zhou, M., “Correlation of increased MALAT1 expression with pathological features and prognosis in cancer patients: a meta-analysis”, vol. 14, pp. 18808-18819, 2015.

Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has been identified as a potential cancer biomarker, yet the mechanism by which it influences the development of cancer remains unknown. In this study, we aimed to correlate MALAT1 expression with pathological features and prognosis in cancer patients. Several databases were searched using combinations of keywords relating to MALAT1 and cancer. After selection of relevant cohort studies according to strict criteria, a meta-analysis was conducted.

Protein expression levels in the medullary visceral zone of rats with subarachnoid hemorrhage

L. H. Sun, Xing, L. F., Zhang, G. H., and Pan, S. Y., “Protein expression levels in the medullary visceral zone of rats with subarachnoid hemorrhage”, vol. 14, pp. 8839-8846, 2015.

We investigated protein expression in the medullary visceral zone (MVZ) of rats with multiple-organ dysfunction syndrome (MODS) caused by subarachnoid hemorrhage (SAH) to discuss the possible regulatory mechanism of the MVZ in the course of SAH-induced MODS. A SAH-induced MODS model was established in rats by injecting arterial blood into the Willis’ circle. Protein expression in the MVZ was analyzed by immunohistochemistry assay. Protein expression in the MVZ peaked 24-36 h after SAH, and was significantly higher than in the control and sham operation groups.

Expression patterns of melatonin receptors in chicken ovarian follicles affected by monochromatic light

D. Y. Li, Wu, N., Tu, J. B., Hu, Y. D., Yang, M. Y., Yin, H. D., Chen, B. L., Xu, H. L., Yao, Y. F., and Zhu, Q., “Expression patterns of melatonin receptors in chicken ovarian follicles affected by monochromatic light”, vol. 14, pp. 10072-10080, 2015.

Artificial illumination is an important exogenous factor in the control of many physiological and behavioral processes as well as an important environmental factor in the management of laying hens. Melatonin receptors are members of the G protein-coupled receptor family. The hormone melatonin is secreted primarily by the pineal gland, with highest levels occurring during the dark period of a circadian cycle. The aim of this study was to examine the effect of monochromatic light on chicken egg reproduction and expression of melatonin receptors in chicken ovarian follicles.

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