Promoter

Association between RASSF1A promoter methylation and renal cell cancer susceptibility: a meta-analysis

Y. Q. Huang, Guan, H., Liu, C. H., Liu, D. C., Xu, B., Jiang, L., Lin, Z. X., Chen, M., Huang, Y. Q., Guan, H., Liu, C. H., Liu, D. C., Xu, B., Jiang, L., Lin, Z. X., Chen, M., Huang, Y. Q., Guan, H., Liu, C. H., Liu, D. C., Xu, B., Jiang, L., Lin, Z. X., and Chen, M., Association between RASSF1A promoter methylation and renal cell cancer susceptibility: a meta-analysis, vol. 15, p. -, 2016.

Epigenetic inactivation of Ras-associated domain family 1A (RASSF1A) by hyper-methylation of its promoter region has been identified in various cancers. However, the role of RASSF1A in renal cancer has neither been thoroughly investigated nor reviewed. In this study, we reviewed and performed a meta-analysis of 13 published studies reporting correlations between methylation frequency of the RASSF1A promoter region and renal cancer risk.

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