Decreased expression of tumor suppressive miR-874 and its clinical significance in human osteosarcoma
“Decreased expression of tumor suppressive miR-874 and its clinical significance in human osteosarcoma”, vol. 14, pp. 18315-18324, 2015.
, Dysregulation of microRNAs (miRs) is associated with cancer development and progression and aberrant expression of miR-874 have been found in some types of cancer. However, the expression and function of miR-874 in osteosarcoma remain unclear. The aim of this study was to explore the effects of miR-874 in osteosarcoma tumorigenesis and development. The expression level of miR-874 was quantified by real-time reverse transcription-polymerase chain reaction (RT-PCR) in human osteosarcoma cell lines and tissues.