Prognosis

Prognostic significance of long non-coding RNA MALAT-1 in various human carcinomas: a meta-analysis

J. Wang, Xu, A. M., Zhang, J. Y., He, X. M., Pan, Y. S., Cheng, G., Qin, C., Hua, L. X., Wang, Z. J., Wang, J., Xu, A. M., Zhang, J. Y., He, X. M., Pan, Y. S., Cheng, G., Qin, C., Hua, L. X., Wang, Z. J., Wang, J., Xu, A. M., Zhang, J. Y., He, X. M., Pan, Y. S., Cheng, G., Qin, C., Hua, L. X., and Wang, Z. J., Prognostic significance of long non-coding RNA MALAT-1 in various human carcinomas: a meta-analysis, vol. 15, p. -, 2016.

The long non-coding RNA MALAT-1 plays an important role in cancer prognosis. The present research aimed to elucidate its precise predictive value in various human carcinomas. A quantitative meta-analysis was performed by searching PubMed, Embase, Web of Science, and Cochrane Library (most recently, January 2015) databases, and extracting data from studies that investigated the association between MALAT-1 expression and survival outcomes in patients of various cancers. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated as a measure of generalized effect.

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