PRLR gene

Identification of SNPs within the PRLR gene and effects on maternal behavior in sheep

L. P. Wang, Geng, R. Q., Zhang, X. N., and Sun, W., Identification of SNPs within the PRLR gene and effects on maternal behavior in sheep, vol. 14, pp. 17536-17543, 2015.

The prolactin receptor gene (PRLR) plays an essential role in maternal behavior. The aim of the study was to detect PRLR mutations in exon 10, using a polymerase chain reaction-single stranded conformation polymorphism method, and to determine the association between mutations in this region with maternal behavior traits in Chinese Hu sheep. Polymorphisms were detected only in the gene region amplified by the primer P3; three genotypes (AA, AB and BB) were observed.

Genetic effect of the prolactin receptor gene on egg production traits in chickens

L. Zhang, Li, D. Y., Liu, Y. P., Wang, Y., Zhao, X. L., and Zhu, Q., Genetic effect of the prolactin receptor gene on egg production traits in chickens, vol. 11, pp. 4307-4315, 2012.

The identification and utilization of potential candidate genes with significant effects on economically important traits have become increasingly important in poultry breeding programs. The prolactin (PRLR) receptor is a specific receptor for prolactin, which is an anterior pituitary peptide hormone involved in various physiological activities and is essential for reproductive success. In chickens, the PRLR gene resides on the Z chromosome. We used a pooled DNA sequencing approach for identifying SNPs of the PRLR gene.

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