Primary gout

Investigation on the association between NLRP3 gene polymorphisms and susceptibility to primary gout

L. F. Wang, Ding, Y. J., Zhao, Q., and Zhang, X. L., Investigation on the association between NLRP3 gene polymorphisms and susceptibility to primary gout, vol. 14, pp. 16410-16414, 2015.

We conducted a case-control study to investigate the association between 3 common NALP3 polymorphisms (rs10754558, rs7512998, and rs12137901) and the susceptibility to primary gout. A total of 320 patients with primary gout and 320 controls were included in this study. The genotyping of NALP3 rs10754558, rs7512998, and rs12137901 were conducted by polymerase chain reaction-restriction fragment length polymorphism.

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