Preimplantation embryo

Localization and expression of histone H2A variants during mouse oogenesis and preimplantation embryo development

B. J. Wu, Dong, F. L., Ma, X. S., Wang, X. G., Lin, F., and Liu, H. L., Localization and expression of histone H2A variants during mouse oogenesis and preimplantation embryo development, vol. 13, pp. 5929-5939, 2014.

Epigenetic modifications of the genome, such as histone H2A variants, ensure appropriate gene activation or silencing during oogenesis and preimplantation embryo development. We examined global localization and expression of the histone H2A variants, including H2A.Bbd, H2A.Z and H2A.X, during mouse oogenesis and preimplantation embryo development. Immunocytochemistry with specific antibodies against various histone H2A variants showed their localization and changes during oogenesis and preimplantation development.

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