Preadipocyte

Role of adiponectin in adipose tissue wound healing

C. E. Jin, Xiao, L., Ge, Z. H., Zhan, X. B., and Zhou, H. X., Role of adiponectin in adipose tissue wound healing, vol. 14, pp. 8883-8891, 2015.

The purpose of this study was to investigate the mechanism behind adipose tissue wound healing (ATWH). The preadipocyte cell line 3T3-L1 was cultured and expression of adiponectin receptors (AdipoR1/2) was detected by immunohistochemistry and reverse transcription polymerase chain reaction. The concentration of adiponectin secreted at different cell densities was measured by enzyme-linked immunosorbent assay, while preadipocyte proliferation and migration were determined in vitro by MTT and wound closure assays. AdipoR1/2 were found to be expressed in 3T3-L1 preadipocytes.

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