PPARD

Positive association between PPARD rs2016520 polymorphism and coronary heart disease in a Han Chinese population

H. D. Ye, Li, Y. R., Hong, Q. X., Zhou, A. N., Zhao, Q. L., Xu, L. M., Xu, M. Q., Xu, X. T., Tang, L. L., Dai, D. J., Jiang, D. J., Huang, Y., Wang, D. W., and Duan, S. W., Positive association between PPARD rs2016520 polymorphism and coronary heart disease in a Han Chinese population, vol. 14, pp. 6350-6359, 2015.

PPARD encodes peroxisome proliferator-activated re­ceptor delta, which has been shown to play an important role in control­ling lipid metabolism and atherosclerosis. In this case-control study, we explored the relationship between PPARD rs2016520 polymorphism and coronary heart disease (CHD) in a Han Chinese population. A to­tal of 657 CHD cases and 640 controls were included in the associa­tion study. rs2016520 polymorphism genotyping was performed using the melting temperature-shift polymerase chain reaction method.

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