Post-traumatic stress disorder

Comparative analysis of platelet 5-HT concentrations in Han and Li patients with post-traumatic stress disorder

L. Li, Li, M. X., Pan, L. H., Wang, G. M., Guo, M., Fu, L. Q., Guo, J. C., Gao, Y. S., Chen, F., Xie, M. X., Li, L., Li, M. X., Pan, L. H., Wang, G. M., Guo, M., Fu, L. Q., Guo, J. C., Gao, Y. S., Chen, F., and Xie, M. X., Comparative analysis of platelet 5-HT concentrations in Han and Li patients with post-traumatic stress disorder, vol. 15, p. -, 2016.

We investigated the role of serotonin (5-HT) in the pathogenesis of post-traumatic stress disorder (PTSD) by determining the platelet 5-HT concentrations in Li and Han patients with PTSD in Hainan Province, China. Li and Han control groups of the same sample size have no statistical differences in gender and age distribution compared to those in the PTSD groups who were also examined. The platelet 5-HT concentrations were determined by high-performance liquid chromatography. In addition, the patients and controls were evaluated by the impact of event scale-revised (IES-R).

Epigenetic mechanism of maternal post-traumatic stress disorder in delayed rat offspring development: dysregulation of methylation and gene expression

X. G. Zhang, Zhang, H., Liang, X. L., Liu, Q., Wang, H. Y., Cao, B., Cao, J., Liu, S., Long, Y. J., Xie, W. Y., Peng, D. Z., Zhang, X. G., Zhang, H., Liang, X. L., Liu, Q., Wang, H. Y., Cao, B., Cao, J., Liu, S., Long, Y. J., Xie, W. Y., and Peng, D. Z., Epigenetic mechanism of maternal post-traumatic stress disorder in delayed rat offspring development: dysregulation of methylation and gene expression, vol. 15, p. -, 2016.

Maternal post-traumatic stress disorder (PTSD) increases the risk of adverse neurodevelopmental outcomes in the child. Epigenetic alternations may play an essential role in the negative effects of PTSD. This study was aimed to investigate the possible epigenetic alterations of maternal PTSD, which underpins the developmental and behavioral impact. 24 pregnant Sprague-Dawley (SD) rats were randomly grouped into PTSD and control groups.

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