Porcine granulosa cells

Effect of BMPRIB gene silencing by siRNA on apoptosis and steroidogenesis of porcine granulosa cells

Y. Y. Zhao, Li, X. X., Wang, W., Chen, X., Yu, P., Wang, J. J., and Xu, Y. X., Effect of BMPRIB gene silencing by siRNA on apoptosis and steroidogenesis of porcine granulosa cells, vol. 13, pp. 9964-9975, 2014.

Bone morphogenetic proteins (BMPs) are the key factors in maintaining cell growth and differentiation in ovaries. BMPs initiate signaling by assembling BMP receptors and activating Smads, which in turn alter the expression of target genes. However, little is known about the effect of the deletion of the Bone morphogenetic protein receptor type IB (BMPRIB) on porcine granulosa cell (GCs).

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