Association between PAI-1 polymorphisms and plasma PAI-1 level with sepsis in severely burned patients
“Association between PAI-1 polymorphisms and plasma PAI-1 level with sepsis in severely burned patients”, vol. 14, pp. 10081-10086, 2015.
, We investigated the association between plasminogen activator inhibitor-1 (PAI-1) polymorphisms and plasma PAI-1 level with sepsis in severely burned patients. A total of 182 patients with burn areas lager than 30% of the body surface area were enrolled in this study. Peripheral blood samples were obtained from 103 patients with sepsis (sepsis group) and 79 patients without sepsis (control group). An allele-specific polymerase chain reaction assay was used to determine PAI-1 polymorphism 4G/5G distribution.