Polymorphism

Predictive potential role of glutathione S-transferase polymorphisms in the prognosis of breast cancer

X. Wang and Huang, Z. H., Predictive potential role of glutathione S-transferase polymorphisms in the prognosis of breast cancer, vol. 14, pp. 10236-10241, 2015.

The current study aimed at evaluating the associa­tion between GSTM1 null/present, GSTT1 null/present, and GSTP1 IIe105Val polymorphisms and clinical response to chemotherapy and treatment outcome of breast cancers patients. Genotyping of GSTP1 rs1695, GSTT1 deletion, and GSTM1 deletion was performed by Polymerase Chain Reaction Restriction Fragment Length Polymor­phism (PCR-RFLP) assay.

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