Polymorphism

Analysis of the prevalence of polymorphisms in the glutathione S transferase gene (GST) in cataract patients from Goiânia

I. R. Costa, Mascarenhas, R. S., Corrêa, J. F., Oliveira, F. R. B., Fernandes, S. G., Souza, F. O., Reis, G. Mdos, A. Júnior, deP. R., Rodrigues, D. A., Martins, J. V. M., Silva, K. S. Fe, Moura, K. K. V. O., Costa, I. R., Mascarenhas, R. S., Corrêa, J. F., Oliveira, F. R. B., Fernandes, S. G., Souza, F. O., Reis, G. Mdos, A. Júnior, deP. R., Rodrigues, D. A., Martins, J. V. M., Silva, K. S. Fe, and Moura, K. K. V. O., Analysis of the prevalence of polymorphisms in the glutathione S transferase gene (GST) in cataract patients from Goiânia, vol. 15, p. -, 2016.

The aim of this study was to determine the prevalence of polymorphisms in the glutathione S-transferase genes GSTM1 and GSTT1 in patients with lens opacity (cataract). Peripheral blood samples were obtained from male and female patients (N = 23) with cataract. The GSTM1 and GSTT1 polymorphic regions were amplified by polymerase chain reaction, and the amplification products were electrophoresed on a 2% agarose gel. The obtained bands were by staining with ethidium bromide.

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