Polymorphism

SNP at miR-483-5p-binding site in the 3'-untranslated region of the BSG gene is associated with susceptibility to esophageal cancer in a Chinese population

H. Y. Li, Liu, Y. C., Bai, Y. H., Sun, M., Wang, L., Zhang, X. B., Cai, B., Li, H. Y., Liu, Y. C., Bai, Y. H., Sun, M., Wang, L., Zhang, X. B., and Cai, B., SNP at miR-483-5p-binding site in the 3'-untranslated region of the BSG gene is associated with susceptibility to esophageal cancer in a Chinese population, vol. 15, p. -, 2016.

The aim of this study was to investigate the association between a functional variant of the basigin (BSG) gene, caused by a polymorphism (rs11473) at the miR-483-5p binding site, and the risk of esophageal squamous cell carcinoma (ESCC) in the Chinese population. The rs11473 polymorphism was genotyped in 624 esophageal cancer patients and 636 cancer-free age- and gender-matched controls using polymerase chain reaction restriction and direct sequencing.

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